Estimation and Control of (Local) False Discovery Rates This package allows to estimate both tail area-based false discovery rates (Fdr) as well as local false discovery rates (fdr) for a variety of null models (p-values, z-scores, correlation coefficients, t-scores). The proportion of null values and the parameters of the null distribution are adaptively estimated from the data. In addition, the package contains functions for non-parametric density estimation (Grenander estimator), for monotone regression (isotonic regression and antitonic regression with weights), for computing the greatest convex minorant (GCM) and the least concave majorant (LCM), and for the half-normal and correlation distributions. Software Depends: R (>= 2.10.0) Korbinian Strimmer <strimmer@uni-leipzig.de> Korbinian Strimmer. GPL (>= 3) 2012-05-27 application/tgz http://CRAN.R-project.org/package=fdrtool