Predict protein-protein interactions based on functional and topological similarities This package implements several functions useful for computing similarities between proteins based on their GO annotation, KEGG annotation and PPI network topology. It integrates these similarities to predict PPIs using an SVM classifier. Twenty species are supported, including Anopheles, Arabidopsis, Bovine, Canine, Chicken, Chimp, E coli strain K12 and strain Sakai, Fly, Human, Malaria, Mouse, Pig, Rhesus, Rat, Worm, Xenopus, Yeast, Streptomyces coelicolor and Zebrafish. Software Depends: R (>= 2.12), AnnotationDbi, GO.db, KEGG.db, org.Sc.sgd.db, igraph, e1071, org.Hs.eg.db, Suggests: org.Ag.eg.db, org.At.tair.db, org.Bt.eg.db, org.Ce.eg.db, org.Cf.eg.db, org.Dm.eg.db, org.Dr.eg.db, org.EcK12.eg.db, org.EcSakai.eg.db, org.Gg.eg.db, org.Mm.eg.db, org.Mmu.eg.db, org.Pf.plasmo.db, org.Pt.eg.db, org.Rn.eg.db, org.Sco.eg.db, org.Ss.eg.db, org.Xl.eg.db Yue Deng <anfdeng@163.com> Yue Deng GPL-2 2012-03-21 application/tgz http://CRAN.R-project.org/package=ppiPre