Optimization Toolkit for Pharmacokinetic-Pharmacodynamic Models CRAN Task View: DifferentialEquations (http://CRAN.R-project.org/view=DifferentialEquations) scaRabee is a port of the Scarabee toolkit originally written as a Matlab-based application. It provides a framework for simulation and optimization of pharmacokinetic-pharmacodynamic models at the individual and population level. It is built on top of the neldermead package, which provides the direct search algorithm proposed by Nelder and Mead for model optimization. Software Depends: neldermead, optimsimplex, optimbase, lattice, grid, deSolve, utils Sebastien Bihorel <sb.pmlab@gmail.com> Sebastien Bihorel GPL-3 2011-12-11 application/tgz http://CRAN.R-project.org/package=scaRabee