CN Profiling using Sequencing and CBS This is a method for DNA Copy Number Profiling using Next-Generation Sequencing. It has new model and test statistics based on non-homogeneous Poisson Processes with change point models. It uses an adaptation of Circular Binary Segmentation. Also included are methods for point-wise Bayesian Confidence Interval and model selection method for the change-point model. A case and a control sample reads (normal and tumor) are required. Software Depends: R (>= 2.10), clue Jeremy J. Shen <jeremyjshen@gmail.com> Jeremy J. Shen, Nancy R. Zhang GPL-2 2011-05-22 application/tgz http://CRAN.R-project.org/package=seqCBS