ARTIVA: Infer a time-varying DBN network from time series data

This package generates Reversible Jump MCMC (RJ-MCMC) sampling for approximating the posterior distribution of a time varying regulatory network, under the Auto Regressive TIme VArying (ARTIVA) model (for a detailed description of the algorithm, see Lebre et al. BMC Systems Biology, 2010). Starting from time-course gene expression measurements for a gene of interest (referred to as "target gene") and a set of genes (referred to as "parent genes") which may explain the expression of the target gene, the ARTIVA procedure identifies temporal segments for which a set of interactions occur between the "parent genes" and the "target gene". The time points that delimit the different temporal segments are referred to as changepoints (CP).

Version: 1.2.2
Depends: MASS, igraph, gplots
Published: 2013-09-09
Author: S. Lebre and G. Lelandais.
Maintainer: S. Lebre <sophie.lebre at>
License: GPL-2 | GPL-3 [expanded from: GPL (≥ 2)]
NeedsCompilation: no
CRAN checks: ARTIVA results


Reference manual: ARTIVA.pdf
Package source: ARTIVA_1.2.2.tar.gz
Windows binaries: r-devel:, r-release:, r-oldrel:
OS X Snow Leopard binaries: r-release: ARTIVA_1.2.2.tgz, r-oldrel: ARTIVA_1.2.2.tgz
OS X Mavericks binaries: r-release: ARTIVA_1.2.2.tgz
Old sources: ARTIVA archive