DoseFinding: Planning and Analyzing Dose Finding Experiments

The DoseFinding package provides functions for the design and analysis of dose-finding experiments (with focus on pharmaceutical Phase II clinical trials). It provides functions for: multiple contrast tests, fitting non-linear dose-response models (using Bayesian and non-Bayesian estimation), calculating optimal designs and an implementation of the MCPMod methodology.

Version: 0.9-15
Depends: lattice, mvtnorm, R (≥ 2.15.0)
Suggests: numDeriv, Rsolnp, quadprog, parallel, multcomp
Published: 2016-07-27
Author: Bjoern Bornkamp, Jose Pinheiro, Frank Bretz
Maintainer: Bjoern Bornkamp <bbnkmp at>
License: GPL-3
NeedsCompilation: yes
Materials: ChangeLog
In views: ClinicalTrials, ExperimentalDesign
CRAN checks: DoseFinding results


Reference manual: DoseFinding.pdf
Package source: DoseFinding_0.9-15.tar.gz
Windows binaries: r-devel:, r-release:, r-oldrel:
OS X Mavericks binaries: r-release: DoseFinding_0.9-15.tgz, r-oldrel: DoseFinding_0.9-15.tgz
Old sources: DoseFinding archive

Reverse dependencies:

Reverse imports: LRcontrast, TestingSimilarity, uniReg