DoseFinding: Planning and Analyzing Dose Finding experiments

The DoseFinding package provides functions for the design and analysis of dose-finding experiments (with focus on pharmaceutical Phase II clinical trials). It provides functions for: multiple contrast tests, fitting non-linear dose-response models (using Bayesian and non-Bayesian estimation), calculating optimal designs and an implementation of the MCPMod methodology.

Version: 0.9-11
Depends: lattice, mvtnorm, R (≥ 3.0.0)
Suggests: numDeriv, Rsolnp, quadprog, multcomp
Published: 2014-02-11
Author: Bjoern Bornkamp, Jose Pinheiro, Frank Bretz
Maintainer: Bjoern Bornkamp <bbnkmp at gmail.com>
License: GPL-3
NeedsCompilation: yes
Materials: ChangeLog
In views: ClinicalTrials, ExperimentalDesign
CRAN checks: DoseFinding results

Downloads:

Reference manual: DoseFinding.pdf
Package source: DoseFinding_0.9-11.tar.gz
OS X binary: DoseFinding_0.9-11.tgz
Windows binary: DoseFinding_0.9-11.zip
Old sources: DoseFinding archive