The DoseFinding package provides functions for the design and analysis of dose-finding experiments (with focus on pharmaceutical Phase II clinical trials). It provides functions for: multiple contrast tests, fitting non-linear dose-response models (using Bayesian and non-Bayesian estimation), calculating optimal designs and an implementation of the MCPMod methodology.
|Depends:||lattice, mvtnorm, R (≥ 2.15.0)|
|Suggests:||numDeriv, Rsolnp, quadprog, parallel, multcomp|
|Author:||Bjoern Bornkamp, Jose Pinheiro, Frank Bretz|
|Maintainer:||Bjoern Bornkamp <bbnkmp at gmail.com>|
|In views:||ClinicalTrials, ExperimentalDesign|
|CRAN checks:||DoseFinding results|
|Windows binaries:||r-devel: DoseFinding_0.9-15.zip, r-release: DoseFinding_0.9-15.zip, r-oldrel: DoseFinding_0.9-15.zip|
|OS X El Capitan binaries:||r-release: DoseFinding_0.9-15.tgz|
|OS X Mavericks binaries:||r-oldrel: DoseFinding_0.9-15.tgz|
|Old sources:||DoseFinding archive|
|Reverse imports:||LRcontrast, TestingSimilarity, uniReg|
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