FAMT: Factor Analysis for Multiple Testing (FAMT) : simultaneous tests under dependence in high-dimensional data

The method proposed in this package takes into account the impact of dependence on the multiple testing procedures for high-throughput data as proposed by Friguet et al. (2009). The common information shared by all the variables is modeled by a factor analysis structure. The number of factors considered in the model is chosen to reduce the false discoveries variance in multiple tests. The model parameters are estimated thanks to an EM algorithm. Adjusted tests statistics are derived, as well as the associated p-values. The proportion of true null hypotheses (an important parameter when controlling the false discovery rate) is also estimated from the FAMT model. Graphics are proposed to interpret and describe the factors.

Version: 2.5
Depends: mnormt, impute
Published: 2014-01-02
Author: David Causeur, Chloe Friguet, Magalie Houee-Bigot, Maela Kloareg
Maintainer: David Causeur <David.Causeur at agrocampus-ouest.fr>
License: GPL-2 | GPL-3 [expanded from: GPL (≥ 2)]
URL: http://famt.free.fr/
NeedsCompilation: no
CRAN checks: FAMT results


Reference manual: FAMT.pdf
Package source: FAMT_2.5.tar.gz
Windows binaries: r-devel: FAMT_2.5.zip, r-release: FAMT_2.5.zip, r-oldrel: FAMT_2.5.zip
OS X El Capitan binaries: r-release: not available
OS X Mavericks binaries: r-oldrel: FAMT_2.5.tgz
Old sources: FAMT archive


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