PSM: Non-Linear Mixed-Effects modelling using Stochastic Differential Equations

This package provides functions for estimation of linear and non-linear mixed-effects models using stochastic differential equations. Moreover it provides functions for finding smoothed estimates of model states and for simulation. The package allows for any multivariate non-linear time-variant model to be specified, and it also handels multidimentional input, co-variates, missing observations and specification of dosage regimen.

Version: 0.8-3
Depends: MASS, numDeriv, odesolve
Date: 2008-09-18
Author: Stig Mortensen and Søren Klim
Maintainer: Authors <psmpackage at imm.dtu.dk>
License: GPL (≥2)
URL: http://www.imm.dtu.dk/psm
CRAN checks: PSM results

Downloads:

Package source: PSM_0.8-3.tar.gz
MacOS X binary: PSM_0.8-3.tgz
Windows binary: PSM_0.8-3.zip
Reference manual: PSM.pdf
Vignettes: Population Stochastic Modelling: Model definition, description and examples
Old sources: PSM archive