Power2Stage: Power and Sample size distribution of 2-stage BE studies via simulations

Contains a function to calculate power and sample size distribution of 2-stage BE studies with a 2x2 crossover design according to Potvin et al. / Montague et al. modified to include a futility Nmax and modified to do the sample size estimation step with PE and mse of stage 1. Contains further a function with the modifications according to Karalis & Macheras which use PE and mse from stage 1 also for the power monitoring steps. The third function power.2stage.fC() calculates power and sample size distribution of 2-stage BE studies with a futility criterion for the point estimator or CI of T/R from stage 1. The fourth function power.2stage.GS() calculates power of non-adaptive group sequential (2-stage) BE studies. The fifth function power.2stage.p() calculates power and sample size distribution of 2-stage BE studies with 2 parallel groups.

Version: 0.1-5
Depends: PowerTOST
Published: 2014-10-10
Author: Detlew Labes [aut, cre], Helmut Schuetz [ctb]
Maintainer: Detlew Labes <DetlewLabes at gmx.de>
License: GPL-2 | GPL-3 [expanded from: GPL (≥ 2)]
NeedsCompilation: no
Materials: NEWS
CRAN checks: Power2Stage results

Downloads:

Reference manual: Power2Stage.pdf
Package source: Power2Stage_0.1-5.tar.gz
Windows binaries: r-devel: Power2Stage_0.1-5.zip, r-release: Power2Stage_0.1-5.zip, r-oldrel: Power2Stage_0.1-5.zip
OS X Snow Leopard binaries: r-release: Power2Stage_0.1-5.tgz, r-oldrel: Power2Stage_0.1-5.tgz
OS X Mavericks binaries: r-release: Power2Stage_0.1-5.tgz
Old sources: Power2Stage archive