Power2Stage: Power and Sample size distribution of 2-stage BE studies via
Contains a function to calculate power and sample size distribution
of 2-stage BE studies with a 2x2 crossover design according to
Potvin et al. / Montague et al. modified to include a futility Nmax
and modified to do the sample size estimation step with PE and mse
of stage 1. Contains further a function with the modifications
according to Karalis & Macheras which use PE and mse from stage 1
also for the power monitoring steps.
The third function power.2stage.fC() calculates power and sample
size distribution of 2-stage BE studies with a futility criterion
for the point estimator or CI of T/R from stage 1.
The fourth function power.2stage.GS() calculates power of non-adaptive
group sequential (2-stage) BE studies.
The fifth function power.2stage.p() calculates power and sample size
distribution of 2-stage BE studies with 2 parallel groups.
||Detlew Labes [aut, cre],
Helmut Schuetz [ctb]
||Detlew Labes <DetlewLabes at gmx.de>
||GPL-2 | GPL-3 [expanded from: GPL (≥ 2)]