Power2Stage: Power and Sample size distribution of 2-stage BE studies via simulations

Contains functions to calculate power and sample size distribution of 2-stage BE studies with a 2x2 crossover design according to Potvin et.al. / Montague et. al. modified to include a futility Nmax and modified to do the sample size estimation step with PE and mse of stage 1 as well as the power calculation steps according to Karalis & Macheras. The third function calculates power and sample size distribution of 2-stage BE studies with a futility criterion for the point estimator of T/R from stage 1. The fourth function calculates power of non-adaptive group sequential (2-stage) BE studies. The fifth function calculates power and sample size distribution of 2-stage BE studies in 2 parallel groups.

Version: 0.1-3
Depends: PowerTOST
Published: 2014-07-02
Author: Detlew Labes [aut, cre], Helmut Schuetz [ctb]
Maintainer: Detlew Labes <DetlewLabes at gmx.de>
License: GPL-2 | GPL-3 [expanded from: GPL (≥ 2)]
NeedsCompilation: no
Materials: NEWS
CRAN checks: Power2Stage results

Downloads:

Reference manual: Power2Stage.pdf
Package source: Power2Stage_0.1-3.tar.gz
Windows binaries: r-devel: Power2Stage_0.1-3.zip, r-release: Power2Stage_0.1-3.zip, r-oldrel: Power2Stage_0.1-3.zip
OS X Snow Leopard binaries: r-release: Power2Stage_0.1-3.tgz, r-oldrel: Power2Stage_0.1-3.tgz
OS X Mavericks binaries: r-release: Power2Stage_0.1-3.tgz
Old sources: Power2Stage archive