RSNPset: Efficient Score Statistics for Genome-Wide SNP Set Analysis

An implementation of the use of efficient score statistics in genome-wide SNP set analysis with complex traits. Three standard score statistics (Cox, binomial, and Gaussian) are provided, but the package is easily extensible to include others. Code implementing the inferential procedure is primarily written in C++ and utilizes parallelization of the analysis to reduce runtime. A supporting function offers simple computation of observed, permutation, and FWER and FDR adjusted p-values.

Version: 0.5
Imports: fastmatch (≥ 1.0-4), foreach (≥ 1.4.1), doRNG (≥ 1.5.3), qvalue (≥ 1.34), Rcpp (≥ 0.10.4)
LinkingTo: Rcpp, RcppEigen
Suggests: knitr
Published: 2015-11-20
Author: Chanhee Yi, Alexander Sibley, and Kouros Owzar
Maintainer: Alexander Sibley <alexander.sibley at>
License: GPL-3
NeedsCompilation: yes
Materials: NEWS
CRAN checks: RSNPset results


Reference manual: RSNPset.pdf
Vignettes: rsnpset
Package source: RSNPset_0.5.tar.gz
Windows binaries: r-devel:, r-release:, r-oldrel:
OS X Snow Leopard binaries: r-release: not available, r-oldrel: RSNPset_0.4.tgz
OS X Mavericks binaries: r-release: RSNPset_0.5.tgz
Old sources: RSNPset archive