SimHap: A comprehensive modeling framework for epidemiological outcomes and a simulation-based approach to haplotypic analysis of population-based data

SimHap is a package for genetic association testing. It can perform single SNP and multi-locus (haplotype) association analyses for continuous Normal, binary, longitudinal and right-censored outcomes measured in population-based samples. SimHap uses estimation maximisation techniques for inferring haplotypic phase in individuals, and incorporates a novel simulation-based approach to deal with the uncertainty of imputed haplotypes in association testing.

Version: 1.2.0
Depends: stats, survival, nlme
Published: 2012-06-21
Author: Pamela A. McCaskie
Maintainer: Matthew Kowgier <matthew.kowgier at oicr.on.ca>
License: GPL-2
NeedsCompilation: no
CRAN checks: SimHap results

Downloads:

Reference manual: SimHap.pdf
Package source: SimHap_1.2.0.tar.gz
Windows binaries: r-devel: SimHap_1.2.0.zip, r-release: SimHap_1.2.0.zip, r-oldrel: SimHap_1.2.0.zip
OS X Snow Leopard binaries: r-release: SimHap_1.2.0.tgz, r-oldrel: SimHap_1.2.0.tgz
OS X Mavericks binaries: r-release: SimHap_1.2.0.tgz
Old sources: SimHap archive