SimHap: A comprehensive modeling framework for epidemiological outcomes
and a simulation-based approach to haplotypic analysis of
SimHap is a package for genetic association testing. It
can perform single SNP and multi-locus (haplotype) association
analyses for continuous Normal, binary, longitudinal and
right-censored outcomes measured in population-based samples.
SimHap uses estimation maximisation techniques for inferring
haplotypic phase in individuals, and incorporates a novel
simulation-based approach to deal with the uncertainty of
imputed haplotypes in association testing.
||stats, survival, nlme
||Pamela A. McCaskie
||Matthew Kowgier <matthew.kowgier at oicr.on.ca>