SmoothHazard is a package for fitting illness-death (and survival) model with possibly interval-censored data for transition toward transient state. Left-truncated and right-censored data are also allowed. Proportional intensities regression models allow for covariates on each of the 3 transitions. We use either a parametric approach with Weibull baseline intensities or a semi-parametric approach with M-splines approximation of baseline intensities in order to obtain smooth estimates. Estimation of parameters is conducted by likelihood maximization in the parametric approach or penalized likelihood maximization in the semi-parametric approach.

Version: | 1.2.3 |

Depends: | R (≥ 1.9.1) |

Imports: | lava, mvtnorm, prodlim |

Published: | 2014-09-19 |

Author: | Celia Touraine, Pierre Joly, Thomas A. Gerds |

Maintainer: | Thomas Alexander Gerds <tag at biostat.ku.dk> |

BugReports: | NA |

License: | GPL-2 | GPL-3 [expanded from: GPL (≥ 2)] |

URL: | NA |

NeedsCompilation: | yes |

In views: | Survival |

CRAN checks: | SmoothHazard results |

Reference manual: | SmoothHazard.pdf |

Package source: | SmoothHazard_1.2.3.tar.gz |

Windows binaries: | r-devel: SmoothHazard_1.2.3.zip, r-release: SmoothHazard_1.2.3.zip, r-oldrel: SmoothHazard_1.2.3.zip |

OS X Mavericks binaries: | r-release: SmoothHazard_1.2.3.tgz, r-oldrel: SmoothHazard_1.2.3.tgz |

Old sources: | SmoothHazard archive |