TEQR: Target Equivalence Range Design

The target equivalence range (TEQR) design, previously named the toxicity equivalence range design is an up-down design patterned after the modified toxicity probability interval design.The TEQR design extends the well known 3+3 design to allow for: an explicit target range for the dose limiting toxicity (DLT) rate, more subjects at the maximum tolerated dose (MTD), and specification of a too-toxic rate, which closes a dose level, In addition, the TEQR design can be implemented to target a dose based either on toxicity rate or activity rate constrained for toxicity.

Version: 2.0-0
Published: 2013-07-09
Author: M. Suzette Blanchard
Maintainer: M. Suzette Blanchard <sblanchard at coh.org>
License: GPL-2
NeedsCompilation: no
In views: ClinicalTrials, ExperimentalDesign
CRAN checks: TEQR results


Reference manual: TEQR.pdf
Package source: TEQR_2.0-0.tar.gz
OS X binary: TEQR_2.0-0.tgz
Windows binary: TEQR_2.0-0.zip
Old sources: TEQR archive