adaptIVPT: Adaptive Bioequivalence Design for In-Vitro Permeation Tests

Contains functions carrying out adaptive procedures using mixed scaling approach to establish bioequivalence for in-vitro permeation test (IVPT) data. Currently, the package provides procedures based on parallel replicate design and balanced data, according to the U.S. Food and Drug Administration's "Draft Guidance on Acyclovir" < cream_RLD 21478_RV12-16.pdf>. Potvin et al. (2008) <doi:10.1002/pst.294> provides the basis for our adaptive design (see Method B). This package reflects the views of the authors and should not be construed to represent the views or policies of the U.S. Food and Drug Administration.

Version: 1.0.0
Depends: R (≥ 3.4)
Imports: Rcpp, rgl
LinkingTo: Rcpp, RcppArmadillo, RcppProgress
Suggests: knitr, rmarkdown
Published: 2022-11-02
Author: Daeyoung Lim [aut, cre], Elena Rantou [ctb], Jessica Kim [ctb], Sungwoo Choi [ctb], Nam Hee Choi [ctb], Stella Grosser [ctb]
Maintainer: Daeyoung Lim <daeyoung.lim at>
License: GPL (≥ 3)
NeedsCompilation: yes
Materials: NEWS
CRAN checks: adaptIVPT results


Reference manual: adaptIVPT.pdf


Package source: adaptIVPT_1.0.0.tar.gz
Windows binaries: r-devel:, r-release:, r-oldrel:
macOS binaries: r-release (arm64): adaptIVPT_1.0.0.tgz, r-oldrel (arm64): adaptIVPT_1.0.0.tgz, r-release (x86_64): adaptIVPT_1.0.0.tgz, r-oldrel (x86_64): adaptIVPT_1.0.0.tgz


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