2013-09-27 Chris Wallace
* v2.3-1
BUGFIX to sdY.est(), now forces zero intercept and stops if
estimated variance is negative.
2013-09-25 Chris Wallace
* v2.3
BUGFIX: Introduced a function to estimate trait variance
from supplied coefficients and standard errors. This is used
within the approach implemented in coloc.abf(), and replaces the
earlier version which implicity assumed that var(Y)=1 for
quantitative traits, which could lead to incorrect inference when
var(Y) was far from 1.
2013-19-06 Chris Wallace
* v2.2
Merged coloc.abf and coloc.abf.imputed(), so that datasets for
wheich beta, var(beta) are available can be matched to datasets
with only p values and maf.2
This means the arguments to coloc.abf() have been changed! Please
check ?coloc.abf for the new function.
2013-03-06 Chris Wallace
* v2.1
Bug fix for coloc.abf() function, which used p12 instead of
log(p12) to calculate L4.
New function coloc.abf.imputed() to make better use of fuller
information on imputed data.
2013-22-05 Chris Wallace
* v2.0
New function, coloc.abf(), to implement the colocalisation
approach described by Giambartolomei et. al.
Changes in the coloc.test() and coloc.bma() functions to make them
consistent with regards arguments and output.
2012-12-10 Chris Wallace
* v1.11
added principal components functions pcs.prepare(), pcs.model().
Restructed the coloc objects to separate Bayesian and non-Bayesian inference.
2012-11-28 Chris Wallace
* v1.10
added Credible Interval calculation to coloc.test().
2012-07-12 Chris Wallace
* v1.09
updated to return u and Var(u) in addition to chisq statistic.
2012-04-12 Chris Wallace
* v1.08
fixed error in documentation, added MASS to Depends.
2012-01-05 Chris Wallace
* v1.06
some tidying.
2012-01-03 Chris Wallace
* v1.05
moved to S4 methods.
2011-12-27 Chris Wallace
* v1.04
made the means of generating plots more flexible.