dcGOR: an R package tailored to the needs of analysing ontologies and
annotations on protein domains
The 'dcGOR' package is intended to provide the wider bioinformatics community with the use of the dcGO database. The dcGO (http://supfam.org/SUPERFAMILY/dcGO) is a comprehensive domain-centric database for annotating protein domains using a variety of ontologies on functions, phenotypes, diseases and more. With the package, users are expected to easily analyse and visualise domain-centric ontologies and annotations. Supported analyses include but are not limited to: easy access to a wide range of ontologies and their domain-centric annotations; enrichment analysis and visual outputs; semantic similarity between annotated domains from ontology term semantic similarity; random walk with restart upon domain-domain (semantic) networks; and high-performance parallel computing.