diskImageR: A Pipeline to Analyze Resistance and Tolerance from Drug Disk Diffusion Assays

A pipeline to analyze photographs of disk diffusion plates. This removes the need to analyze the plates themselves, and thus analysis can be done separate from the assay. Furthermore, diskImageR removes potential researcher bias, by quantitative assessment of drug resistance as the zone diameter at multiple cutoff values of growth inhibition. This method also extends the disk diffusion assay by measuring drug tolerance (in addition to drug resistance) as the fraction of the subpopulation that is able to grow above the resistance point ("FoG"), and drug sensitivity as the rate of change from no growth to full growth ("slope").

Version: 1.0.0
Depends: R (≥ 3.0.3)
Imports: zoo, subplex, tcltk, methods
Suggests: knitr
Published: 2016-04-03
Author: Aleeza Gerstein [aut, cre], Inbal Hecht [ctb]
Maintainer: Aleeza Gerstein <gerst035 at umn.edu>
License: GPL-3
NeedsCompilation: no
SystemRequirements: ImageJ (all OS), Xcode (Mac)
Materials: README
CRAN checks: diskImageR results


Reference manual: diskImageR.pdf
Package source: diskImageR_1.0.0.tar.gz
Windows binaries: r-devel: diskImageR_1.0.0.zip, r-release: diskImageR_1.0.0.zip, r-oldrel: diskImageR_1.0.0.zip
OS X El Capitan binaries: r-release: diskImageR_1.0.0.tgz
OS X Mavericks binaries: r-oldrel: diskImageR_1.0.0.tgz


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