drsmooth: Dose-Response Modeling with Smoothing Splines

Provides tools for assessing the shape of a dose-response curve by testing linearity and non-linearity at user-defined cut-offs. It also provides two methods of estimating a threshold dose, or the dose at which the dose-response function transitions to significantly increasing: bi-linear (based on pkg 'segmented') and smoothed with splines (based on pkg 'mgcv').

Version: 1.9.0
Depends: R (≥ 3.0.1)
Imports: boot, car, mgcv, multcomp, DTK, segmented, lubridate, pgirmess, stats
Suggests: testthat
Published: 2015-09-25
Author: Greg Hixon [aut], Chad Thompson [aut], Anne Bichteler [aut, cre], Liz Abraham [ctb]
Maintainer: Anne Bichteler <abichteler at toxstrategies.com>
License: GPL (≥ 3)
NeedsCompilation: no
Citation: drsmooth citation info
Materials: NEWS
CRAN checks: drsmooth results


Reference manual: drsmooth.pdf
Package source: drsmooth_1.9.0.tar.gz
Windows binaries: r-devel: drsmooth_1.9.0.zip, r-release: drsmooth_1.9.0.zip, r-oldrel: drsmooth_1.9.0.zip
OS X Snow Leopard binaries: r-release: drsmooth_1.0.tgz, r-oldrel: drsmooth_1.0.tgz
OS X Mavericks binaries: r-release: drsmooth_1.9.0.tgz
Old sources: drsmooth archive