epoc: EPoC (Endogenous Perturbation analysis of Cancer)

Estimates sparse matrices A or G using fast lasso regression from mRNA transcript levels Y and CNA profiles U. Two models are provided, EPoC A where AY + U + R = 0 and EPoC G where Y = GU + E, the matrices R and E are so far treated as noise. For details see the reference and the manual page of ‘lassoshooting’.

Version: 0.2.5-1
Depends: R (≥ 2.12.0), lassoshooting (≥ 0.1.4), Matrix, methods, graph
Imports: irr, elasticnet, survival, Rgraphviz
Suggests: RCytoscape
Published: 2013-08-26
Author: Rebecka Jornsten, Tobias Abenius, Sven Nelander
Maintainer: Tobias Abenius <Tobias.Abenius at Chalmers.se>
License: LGPL-3
NeedsCompilation: no
Materials: ChangeLog
CRAN checks: epoc results


Reference manual: epoc.pdf
Package source: epoc_0.2.5-1.tar.gz
Windows binaries: r-devel: epoc_0.2.5-1.zip, r-release: epoc_0.2.5-1.zip, r-oldrel: epoc_0.2.5-1.zip
OS X Mavericks binaries: r-release: epoc_0.2.5-1.tgz, r-oldrel: epoc_0.2.5-1.tgz
Old sources: epoc archive