epoc: EPoC (Endogenous Perturbation analysis of Cancer)

Estimates sparse matrices A or G using fast lasso regression from mRNA transcript levels Y and CNA profiles U. Two models are provided, EPoC A where AY + U + R = 0 and EPoC G where Y = GU + E, the matrices R and E are so far treated as noise. For details see the reference and the manual page of ‘lassoshooting’.

Version: 0.2.4-14
Depends: R (≥ 2.12.0), lassoshooting (≥ 0.1.4), Matrix, methods, irr, igraph0, elasticnet, survival
Suggests: graph, RCytoscape
Published: 2012-10-05
Author: Rebecka Jornsten, Tobias Abenius, Sven Nelander
Maintainer: Tobias Abenius <Tobias.Abenius at Chalmers.se>
License: LGPL-3 (see file LICENSE)
NeedsCompilation: no
CRAN checks: epoc results

Downloads:

Package source: epoc_0.2.4-14.tar.gz
MacOS X binary: epoc_0.2.4-14.tgz
Windows binary: epoc_0.2.4-14.zip
Reference manual: epoc.pdf
News/ChangeLog:ChangeLog
Old sources: epoc archive