falconx: Finding Allele-Specific Copy Number in Whole-Exome Sequencing Data

This is a method for Allele-specific DNA Copy Number profiling for whole-Exome sequencing data. Given the allele-specific coverage and site biases at the variant loci, this program segments the genome into regions of homogeneous allele-specific copy number. It requires, as input, the read counts for each variant allele in a pair of case and control samples, as well as the site biases. For detection of somatic mutations, the case and control samples can be the tumor and normal sample from the same individual. The implemented method is based on the paper: Chen, H., Jiang, Y., Maxwell, K., Nathanson, K. and Zhang, N. (under review). Allele-specific copy number estimation by whole Exome sequencing.

Version: 0.2
Depends: R (≥ 3.0.1)
Published: 2017-02-24
Author: Hao Chen and Nancy R. Zhang
Maintainer: Hao Chen <hxchen at ucdavis.edu>
License: GPL-2 | GPL-3 [expanded from: GPL (≥ 2)]
NeedsCompilation: yes
CRAN checks: falconx results


Reference manual: falconx.pdf
Package source: falconx_0.2.tar.gz
Windows binaries: r-devel: falconx_0.2.zip, r-release: falconx_0.2.zip, r-oldrel: falconx_0.2.zip
OS X El Capitan binaries: r-release: falconx_0.2.tgz
OS X Mavericks binaries: r-oldrel: falconx_0.2.tgz
Old sources: falconx archive


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