famSKATRC: Family Sequence Kernel Association Test for Rare and Common Variants

FamSKAT-RC is a family-based association kernel test for both rare and common variants. This test is general and several special cases are known as other methods: famSKAT, which only focuses on rare variants in family-based data, SKAT, which focuses on rare variants in population-based data (unrelated individuals), and SKAT-RC, which focuses on both rare and common variants in population-based data. When one applies famSKAT-RC and sets the value of phi to 1, famSKAT-RC becomes famSKAT. When one applies famSKAT-RC and set the value of phi to 1 and the kinship matrix to the identity matrix, famSKAT-RC becomes SKAT. When one applies famSKAT-RC and set the kinship matrix (fullkins) to the identity matrix (and phi is not equal to 1), famSKAT-RC becomes SKAT-RC. We also include a small sample synthetic pedigree to demonstrate the method with. For more details see Saad M and Wijsman EM (2014) <doi:10.1002/gepi.21844>.

Version: 1.1.0
Depends: R (≥ 3.4.1)
Imports: CompQuadForm, kinship2, coxme, bdsmatrix
Published: 2017-11-09
Author: Khalid B. Kunji [aut, cre], Mohamad Saad [aut]
Maintainer: Khalid B. Kunji <kkunji at hbku.edu.qa>
License: GPL (≥ 3)
URL: https://www.r-project.org, https://www.ncbi.nlm.nih.gov/pubmed/25132070
NeedsCompilation: no
CRAN checks: famSKATRC results


Reference manual: famSKATRC.pdf
Package source: famSKATRC_1.1.0.tar.gz
Windows binaries: r-devel: famSKATRC_1.1.0.zip, r-release: famSKATRC_1.1.0.zip, r-oldrel: not available
OS X El Capitan binaries: r-release: famSKATRC_1.1.0.tgz
OS X Mavericks binaries: r-oldrel: not available
Old sources: famSKATRC archive


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