L. Kluge, W. Brannath and M. Scharpenberg

## Introduction

informativeSCI can be used for calculating informative lower
simultaneous confidence bounds for a given graphical test procedure and
given information weights. Furthermore, it can help to find the right
information weights for the bounds.

## Installation

You can install the development version from GitHub by running

```
install.packages("devtools")
library(devtools)
install_github("LianeKluge/informativeSCI")
```

Otherwise just use the current version from CRAN.

## Usage

The main function of the package is the
`informSCI`

-function for calculating informative lower
simultaneous confidence bounds for a given graphical test procedure and
given information weights. The `explore_q`

-function can help
to find the right information weights for the
`informSCI`

-algorithm. The `inExactSCI`

- and
`notInExactSCI`

-functions can help to determine how accurate
a (numerical) approximation of the true informative lower SCI-bounds is.
For examples, see the Example sections of the documentation pages.

### References

F. Bretz, W. Maurer, W. Brannath, M. Posch: A graphical approach
to sequentially rejective multiple test procedures. Statistics in
Medicine 28.4 (2009), pp. 586-604.

K. Strassburger, F. Bretz: Compatible simultaneous lower
confidence bounds for the Holm procedure and other Bonferroni based
closed tests. Statistics in Medicine 27.4 (2008),
pp. 4914-4927.

W. Brannath, L. Kluge, M. Scharpenberg: Informative Simultaneous
Confidence Intervals for Graphical Test Procedures. arXiv preprint
arXiv:2402.13719 (2024).

S. Schmidt, W. Brannath: Informative Simultaneous Confidence
Intervals in Hierarchical Testing. Methods of Information in Medicine
53.4 (2014), pp. 278–283.