mixOmics: Omics Data Integration Project

The package supplies two efficients methodologies: regularized CCA and sparse PLS to unravel relationships between two heterogeneous data sets of size (nxp) and (nxq) where the p and q variables are measured on the same samples or individuals n. These data may come from high throughput technologies, such as omics data (e.g. transcriptomics, metabolomics or proteomics data) that require an integrative or joint analysis. However, mixOmics can also be applied to any other large data sets where p + q >> n. rCCA is a regularized version of CCA to deal with the large number of variables. sPLS allows variable selection in a one step procedure and two frameworks are proposed: regression and canonical analysis. Numerous graphical outputs are provided to help interpreting the results.

Version: 3.0
Depends: R (≥ 2.10), igraph, rgl, lattice
Published: 2011-08-11
Author: Sebastien Dejean, Ignacio Gonzalez, Kim-Anh Le Cao, Pierre Monget and Jeff Coquery
Maintainer: Kim-Anh Le Cao <k.lecao at uq.edu.au>
License: GPL (≥ 2)
CRAN checks: mixOmics results

Downloads:

Package source: mixOmics_3.0.tar.gz
MacOS X binary: mixOmics_3.0.tgz
Windows binary: mixOmics_3.0.zip
Reference manual: mixOmics.pdf
News/ChangeLog:NEWS
Old sources: mixOmics archive

Reverse dependencies:

Reverse depends: integrativeME