Version 1.1 Changelog: Major: A vignette (postgwasVignette) has been added. GenABEL, GEMMA and FAsT-LMM output can be read by default. buffer data concept changed (see help(postgwasBuffer)). gwas2network: The legend of graphs can now be plotted to a separate box (new default) gwas2network: Major change in community p-value calculations and GO enrichment (see documentation) gwas2network: topGO enrichment tree can now be plotted (depending on file.verbosity argument) gwas2network: singleton, unconnected vertices now remain part of the network gwas2network: Improved runtime and memory consumption (e.g. uses data.tables) Manhattanplot: Bug on sorting chromosomes with mixed character / numerical values fixed Manhattanplot: Bug for identifying highlighted regions with multiple thresholds fixed Manhattanplot: Gene annotation now draws SNP identifier when no genes can be annotated Manhattanplot: Can draw calibration lines now (argument highlight.lines) getGenotypes: Extended, now also handles GenABEL (gwaa) files getGenotypes: Extended, can now write retrieved genotypes to ped/map and gwaa/phe files getGenotypes: Default argument list and return value definition has been changed Snp2gene: Argument list changed RemoveNeighborSnps: Bugfix in p-value pruning version for certain overlapping region constellations getInteractions: getInteractions.ppi has been removed due to unavailability of the REST access to biogrid. A new getInteractions.path function has been added to generate networks of pathway data from REACTOME biomart. Minor: Manhattanplot: Proportions and scaling of graphical elements optimized Snp2gene: Bugfix for reporting table biomartAccess: downloaded GO terms can now be buffered