This is a method for DNA Copy Number Profiling using Next-Generation Sequencing. It has new model and test statistics based on non-homogeneous Poisson Processes with change point models. It uses an adaptation of Circular Binary Segmentation. Also included are methods for point-wise Bayesian Confidence Interval and model selection method for the change-point model. A case and a control sample reads (normal and tumor) are required.
|Depends:||R (≥ 2.10), clue|
|Author:||Jeremy J. Shen, Nancy R. Zhang|
|Maintainer:||Jeremy J. Shen <jeremyjshen at gmail.com>|
|CRAN checks:||seqCBS results|
|Windows binaries:||r-devel: seqCBS_1.2.zip, r-release: seqCBS_1.2.zip, r-oldrel: seqCBS_1.2.zip|
|OS X Mavericks binaries:||r-release: seqCBS_1.2.tgz, r-oldrel: seqCBS_1.2.tgz|
|Old sources:||seqCBS archive|
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