sp23design: Design and Simulation of seamless Phase II-III Clinical Trials

Provides methods for generating, exploring and executing seamless Phase II-III designs of Lai, Lavori and Shih using generalized likelihood ratio statistics. Includes pdf and source files that describe the entire R implementation with the relevant mathematical details.

Version: 0.9
Depends: R (≥ 3.0), mvtnorm, survival
Suggests: RUnit
Published: 2014-06-26
Author: Balasubramanian Narasimhan [aut, cre], Mei-Chiung Shih [aut], Pei He [aut]
Maintainer: Balasubramanian Narasimhan <naras at stat.stanford.edu>
License: LGPL-3
NeedsCompilation: no
Materials: ChangeLog
CRAN checks: sp23design results

Downloads:

Reference manual: sp23design.pdf
Package source: sp23design_0.9.tar.gz
Windows binaries: r-devel: sp23design_0.9.zip, r-release: sp23design_0.9.zip, r-oldrel: sp23design_0.9.zip
OS X Snow Leopard binaries: r-release: sp23design_0.9.tgz, r-oldrel: sp23design_0.9.tgz
OS X Mavericks binaries: r-release: sp23design_0.9.tgz