tdm: Data Analysis for Therapeutic Drug Monitoring

Therapeutic Drug Monitoring (TDM) is designed to estimate individual pharmacokinetic parameters with one or more drug serum/plasma concentrations obtained from a single subject or multiple subjects using a Bayesian inference porgram, JAGS (Just Another Gibbs Sampling; a computer program for analysis of Bayesian hierarchical models using Markov Chain Monte Carlo simulation), interfaced with rjags. Besides, it also can calculate a suggested dose based on the target drug concentration (C ->D) or calculate a predicted drug concentration with a given dose (D -> C).

Version: 3.0.3
Depends: R (≥ 2.12.0)
Imports: rjags, coda, png, grid, deSolve
Published: 2014-12-16
Author: Miou-ting Chen, Yung-jin Lee
Maintainer: Yung-jin Lee <mobilepk at>
License: GPL-2 | GPL-3 [expanded from: GPL (≥ 2)]
NeedsCompilation: no
Materials: NEWS
In views: ClinicalTrials
CRAN checks: tdm results


Reference manual: tdm.pdf
Package source: tdm_3.0.3.tar.gz
Windows binaries: r-devel:, r-release:, r-oldrel:
OS X Snow Leopard binaries: r-release: tdm_3.0.3.tgz, r-oldrel: tdm_3.0.3.tgz
OS X Mavericks binaries: r-release: tdm_3.0.3.tgz
Old sources: tdm archive