Response surface methods for drug synergy analysis. Available methods include generalized and classical Loewe formulations as well as Highest Single Agent methodology. Response surfaces can be plotted in an interactive 3-D plot and formal statistical tests for presence of synergistic effects are available.
| Version: | 1.0.1 |
| Depends: | R (≥ 2.10) |
| Imports: | ggplot2, MASS, methods, minpack.lm, numDeriv, parallel, progress, rgl, robustbase, scales |
| Suggests: | knitr, testthat, shiny, DT |
| Published: | 2017-06-30 |
| Author: | Heather Turner, Annelies Tourny, Olivier Thas, Maxim Nazarov, Rytis Bagdziunas |
| Maintainer: | Rytis Bagdziunas <rytis.bagdziunas at openanalytics.eu> |
| BugReports: | https://github.com/openanalytics/BIGL/issues |
| License: | GPL-3 |
| URL: | https://github.com/openanalytics/BIGL |
| NeedsCompilation: | no |
| Materials: | NEWS |
| CRAN checks: | BIGL results |
| Reference manual: | BIGL.pdf |
| Vignettes: |
Synergy analysis Methodology |
| Package source: | BIGL_1.0.1.tar.gz |
| Windows binaries: | r-devel: BIGL_1.0.1.zip, r-release: BIGL_1.0.1.zip, r-oldrel: BIGL_1.0.1.zip |
| OS X El Capitan binaries: | r-release: BIGL_1.0.1.tgz |
| OS X Mavericks binaries: | r-oldrel: BIGL_1.0.1.tgz |
Please use the canonical form https://CRAN.R-project.org/package=BIGL to link to this page.