Purpose of this package is it to plan, monitor and evaluate oncological phase II studies. In general this kind of studies are single-arm trials with planned interim analysis and binary endpoint. To meet the resulting requirements, the package provides functions to calculate and evaluate 'Simon's two-stage designs' and 'so-called' 'subset designs'. If you are unfamiliar with this package a good starting point is to take a closer look at the functions getSolutions() and getSolutionsSub1().The web-based tool (https://imbi.shinyapps.io/phaseII-app/) extends the functionality of our R package by means of a proper dealing with over- and underrunning. The R function binom.test of the 'stats' R package and the package 'binom' might be helpful to assess the performance of the corresponding one-stage design as a reference.
|Depends:||methods, stats, Rcpp (≥ 0.9.11), R (≥ 3.1.0)|
|Maintainer:||Marius Wirths <wirths at imbi.uni-heidelberg.de>|
|License:||GPL-2 | GPL-3 [expanded from: GPL (≥ 2)]|
|CRAN checks:||OneArmPhaseTwoStudy results|
|Windows binaries:||r-devel: OneArmPhaseTwoStudy_0.1.6.zip, r-release: OneArmPhaseTwoStudy_0.1.6.zip, r-oldrel: OneArmPhaseTwoStudy_0.1.6.zip|
|OS X Mavericks binaries:||r-release: OneArmPhaseTwoStudy_0.1.6.tgz, r-oldrel: OneArmPhaseTwoStudy_0.1.6.tgz|
|Old sources:||OneArmPhaseTwoStudy archive|
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