OneArmPhaseTwoStudy: Planning, Conducting, and Analysing Single-Arm Phase II Studies

Purpose of this package is it to plan, monitor and evaluate oncological phase II studies. In general this kind of studies are single-arm trials with planned interim analysis and binary endpoint. To meet the resulting requirements, the package provides functions to calculate and evaluate 'Simon's two-stage designs' and 'so-called' 'subset designs'. If you are unfamiliar with this package a good starting point is to take a closer look at the functions getSolutions() and getSolutionsSub1().The web-based tool (<https://imbi.shinyapps.io/phaseII-app/>) extends the functionality of our R package by means of a proper dealing with over- and underrunning. The R function binom.test of the 'stats' R package and the package 'binom' might be helpful to assess the performance of the corresponding one-stage design as a reference.

Version: 1.0.3
Depends: methods, stats, Rcpp (≥ 0.9.11), R (≥ 3.1.0)
LinkingTo: Rcpp
Published: 2017-11-13
Author: Marius Wirths
Maintainer: Johannes Krisam <krisam at imbi.uni-heidelberg.de>
License: GPL-2 | GPL-3 [expanded from: GPL (≥ 2)]
NeedsCompilation: yes
Citation: OneArmPhaseTwoStudy citation info
CRAN checks: OneArmPhaseTwoStudy results

Downloads:

Reference manual: OneArmPhaseTwoStudy.pdf
Package source: OneArmPhaseTwoStudy_1.0.3.tar.gz
Windows binaries: r-devel: OneArmPhaseTwoStudy_1.0.3.zip, r-release: OneArmPhaseTwoStudy_1.0.3.zip, r-oldrel: OneArmPhaseTwoStudy_1.0.3.zip
OS X El Capitan binaries: r-release: OneArmPhaseTwoStudy_1.0.3.tgz
OS X Mavericks binaries: r-oldrel: OneArmPhaseTwoStudy_1.0.3.tgz
Old sources: OneArmPhaseTwoStudy archive

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