PhenotypeSimulator: Flexible Phenotype Simulation from Different Genetic and Noise Models

Phenotype simulator allows for the flexible simulation of phenotypes under different models, including fixed and background genetic effects as well as correlated, fixed and background noise effects. Different phenotypic effects can be combined into a final phenotype while controling for the proportion of variance explained by each of the components. For each component, the number of variables, their distribution and the design of their effect across traits can be customised. The final simulated phenotypes and its components can be automatically saved into .rds or .csv files. In addition, for simulated genotypes, export into plink format is possible.

Version: 0.1.2
Depends: R (≥ 3.3.2)
Imports: methods, optparse, R.utils, plyr, mvtnorm, snpStats, Rcpp (≥ 0.12.11)
LinkingTo: Rcpp
Suggests: testthat, knitr, rmarkdown
Published: 2017-06-12
Author: Hannah Meyer [aut, cre], Konrad Rudolph [ctb]
Maintainer: Hannah Meyer <hannah at ebi.ac.uk>
BugReports: https://github.com/HannahVMeyer/PhenotypeSimulator/issues
License: MIT + file LICENSE
URL: https://github.com/HannahVMeyer/PhenotypeSimulator
NeedsCompilation: yes
Materials: README
CRAN checks: PhenotypeSimulator results

Downloads:

Reference manual: PhenotypeSimulator.pdf
Vignettes: Flexible phenotype simulation with PhenotypeSimulator
Package source: PhenotypeSimulator_0.1.2.tar.gz
Windows binaries: r-devel: PhenotypeSimulator_0.1.2.zip, r-release: PhenotypeSimulator_0.1.2.zip, r-oldrel: PhenotypeSimulator_0.1.2.zip
OS X El Capitan binaries: r-release: not available
OS X Mavericks binaries: r-oldrel: PhenotypeSimulator_0.1.2.tgz
Old sources: PhenotypeSimulator archive

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