RapidoPGS: A Fast and Light Package to Compute Polygenic Risk Scores

Quickly computes polygenic scores from GWAS summary statistics of either case-control or quantitative traits, without LD matrix computation or parameter tuning. Reales,G., Kelemen,M., Wallace,C. (2020) <doi:10.1101/2020.07.24.220392> "RápidoPGS: A rapid polygenic score calculator for summary GWAS data without validation dataset".

Version: 1.0.2
Depends: R (≥ 3.6.0), data.table, RCurl, curl
Imports: GenomicRanges, IRanges, bigsnpr
Suggests: knitr, rmarkdown
Published: 2020-08-07
Author: Guillermo Reales ORCID iD [aut, cre], Chris Wallace ORCID iD [aut], Olly Burren ORCID iD [ctb]
Maintainer: Guillermo Reales <gr440 at cam.ac.uk>
License: GPL-3
NeedsCompilation: no
Materials: README NEWS
CRAN checks: RapidoPGS results

Downloads:

Reference manual: RapidoPGS.pdf
Vignettes: Computing a PGS using RápidoPGS and GWAS catalog
Package source: RapidoPGS_1.0.2.tar.gz
Windows binaries: r-devel: RapidoPGS_1.0.2.zip, r-release: RapidoPGS_1.0.2.zip, r-oldrel: RapidoPGS_1.0.2.zip
macOS binaries: r-release: RapidoPGS_1.0.2.tgz, r-oldrel: not available

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