RxODE: Facilities for Simulating from ODE-Based Models

Facilities for running simulations from ordinary differential equation (ODE) models, such as pharmacometrics and other compartmental models. A compilation manager translates the ODE model into C, compiles it, and dynamically loads the object code into R for improved computational efficiency. An event table object facilitates the specification of complex dosing regimens (optional) and sampling schedules. NB: The use of this package requires both C and Fortran compilers, for details on their use with R please see Section 6.3, Appendix A, and Appendix D in the "R Administration and Installation" manual. Also the code is mostly released under GPL. The VODE and LSODA are in the public domain. The information is available in the inst/COPYRIGHTS.

Version: 0.8.0-8
Depends: R (≥ 3.3.0)
Imports: utils, methods, digest, rex, dparser (≥ 0.1.8), brew, memoise, magrittr, Rcpp (≥ 0.12.3), inline, Matrix, R.utils, PreciseSums (≥ 0.3), n1qn1 (≥ 6.0.1-2), mvnfast, cli, crayon
LinkingTo: dparser (≥ 0.1.8), Rcpp (≥ 0.12.3), RcppArmadillo (≥ 0.5.600.2.0), PreciseSums (≥ 0.3)
Suggests: knitr, nlme, shiny, tcltk, testthat, devtools, covr, rmarkdown, SnakeCharmR, rSymPy, dplyr, tidyr, tibble, curl, ggplot2, gridExtra, microbenchmark, scales, stringi, htmltools, reticulate
Published: 2018-09-25
Author: Matthew L. Fidler [aut], Melissa Hallow [aut], Wenping Wang [aut, cre], Zufar Mulyukov [ctb], Justin Wilkins [ctb], Simon Frost [ctb], Heng Li [ctb], Yu Feng [ctb], Alan Hindmarsh [ctb], Linda Petzold [ctb], Ernst Hairer [ctb], Gerhard Wanner [ctb], Johannes Pfeifer [ctb], Robert B. Schnabel [ctb], Elizabeth Eskow [ctb], J Colinge [ctb], Hadley Wickham [ctb], G Grothendieck [ctb], Robert Gentleman [ctb], Ross Ihaka [ctb], R core team [cph], odepack authors [cph]
Maintainer: Wenping Wang <wwang8198 at gmail.com>
BugReports: https://github.com/nlmixrdevelopment/RxODE/issues
License: GPL-2 | GPL-3 [expanded from: GPL (≥ 2)]
Copyright: see file COPYRIGHTS
URL: https://www.r-project.org, https://github.com/nlmixrdevelopment/RxODE
NeedsCompilation: yes
Citation: RxODE citation info
CRAN checks: RxODE results

Downloads:

Reference manual: RxODE.pdf
Vignettes: RxODE Covariates
RxODE data frames
RxODE Event Coding
Introduction to RxODE
RxODE Solved Systems and ODEs
RxODE and Shiny
RxODE Simulation
RxODE Jacobian specification and Stiff Systems
RxODE ODE solving syntax
RxODE Transit Compartment Models
Package source: RxODE_0.8.0-8.tar.gz
Windows binaries: r-devel: RxODE_0.8.0-8.zip, r-release: RxODE_0.8.0-8.zip, r-oldrel: RxODE_0.8.0-8.zip
OS X binaries: r-release: RxODE_0.8.0-8.tgz, r-oldrel: RxODE_0.8.0-8.tgz
Old sources: RxODE archive

Reverse dependencies:

Reverse imports: nlmixr

Linking:

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