VNM: Finding Multiple-Objective Optimal Designs for the 4-Parameter Logistic Model

Provide tools for finding multiple-objective optimal designs for estimating the shape of dose-response, the ED50 (the dose producing an effect midway between the expected responses at the extreme doses) and the MED (the minimum effective dose level) for the 2,3,4-parameter logistic models and for evaluating its efficiencies for the three objectives. The acronym VNM stands for V-algorithm using Newton Raphson method to search multiple-objective optimal design.

Version: 5.1
Depends: methods
Imports: graphics, Rcpp
LinkingTo: Rcpp
Published: 2017-06-28
Author: Seung Won Hyun, Weng Kee Wong, and Yarong Yang
Maintainer: Yarong Yang <yarongyang78 at>
License: GPL-2 | GPL-3 [expanded from: GPL (≥ 2)]
NeedsCompilation: yes
In views: ExperimentalDesign
CRAN checks: VNM results


Reference manual: VNM.pdf
Package source: VNM_5.1.tar.gz
Windows binaries: r-devel:, r-release:, r-oldrel:
OS X El Capitan binaries: r-release: VNM_4.1.tgz
OS X Mavericks binaries: r-oldrel: VNM_4.1.tgz
Old sources: VNM archive


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