Perform fast queries in R against a massive database of complete GWAS summary data

Lifecycle: stable R build status Codecov test coverage CRAN status r-universe

The OpenGWAS database comprises over 50,000 curated, QC’d and harmonised complete GWAS summary datasets and can be queried using an API. See here for documentation on the API itself. This R package is a wrapper to make generic calls to the API, plus convenience functions for specific queries.

Methods currently implemented:

There are a few convenience functions also:

See for information about how to connect the genotype and LD data to other packages involving colocalisation, finemapping, visualisation and MR.


Install from CRAN using:


or install the developer version of ieugwasr with:


Browse the vignettes etc for information on how to use this package: