medScan: Large Scale Single Mediator Hypothesis Testing

A collection of methods for large scale single mediator hypothesis testing. The six included methods for testing the mediation effect are Sobel's test, Max P test, joint significance test under the composite null hypothesis, high dimensional mediation testing, divide-aggregate composite null test, and Sobel's test under the composite null hypothesis. Du, J., Zhou, X., Hao, W., Liu, Y., Smith, J. A., & Mukherjee, B (2022) "Methods for Large-scale Single Mediator Hypothesis Testing: Possible Choices and Comparisons." arXiv preprint <arXiv:2203.13293>.

Version: 1.0.1
Depends: R (≥ 3.5)
Imports: HDMT, locfdr, qqman, qvalue, fdrtool
Suggests: knitr, rmarkdown
Published: 2022-10-05
Author: Jiacong Du [aut], Michael Kleinsasser [cre]
Maintainer: Michael Kleinsasser <mkleinsa at>
License: GPL-3
NeedsCompilation: no
Materials: README
CRAN checks: medScan results


Reference manual: medScan.pdf


Package source: medScan_1.0.1.tar.gz
Windows binaries: r-devel:, r-release:, r-oldrel:
macOS binaries: r-release (arm64): medScan_1.0.1.tgz, r-oldrel (arm64): medScan_1.0.1.tgz, r-release (x86_64): medScan_1.0.1.tgz, r-oldrel (x86_64): medScan_1.0.1.tgz


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