Conduct multi-locus GWAS and multi-locus QTL mapping under the framework of random-SNP-effect mixed linear model (mrMLM). First, each position (or marker) on the genome is scanned by mrMLM algorithm. Bonferroni correction is replaced by a less stringent selection criterion for significant test. Then, all the markers (or QTL) that are potentially associated with the trait are included in a multi-locus model, their effects are estimated by empirical Bayes and true QTN or QTL are identified by likelihood ratio test.
|Depends:||gWidgets, gWidgetsRGtk2, RGtk2Extras, MASS|
|Imports:||RGtk2, methods, openxlsx, stringr, qqman, ggplot2, lars, ncvreg|
|Author:||Wenlong Ren,Yuanli Ni,Shibo Wang,Yangjun Wen,Bo Huang and Yuanming Zhang|
|Maintainer:||Yuanming Zhang <soyzhang at mail.hzau.edu.cn>|
|License:||GPL-2 | GPL-3 [expanded from: GPL (≥ 2)]|
|CRAN checks:||mrMLM results|
|Windows binaries:||r-devel: mrMLM_2.1.zip, r-release: mrMLM_2.1.zip, r-oldrel: mrMLM_2.1.zip|
|OS X Mavericks binaries:||r-release: mrMLM_2.1.tgz, r-oldrel: mrMLM_2.1.tgz|
|Old sources:||mrMLM archive|
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