mtdesign: Mander and Thompson Designs

Implements Mander & Thompson's (2010) <doi:10.1016/j.cct.2010.07.008> methods for two-stage designs optimal under the alternative hypothesis for phase II [cancer] trials. Also provides an implementation of Simon's (1989) <doi:10.1016/0197-2456(89)90015-9> original methodology and allows exploration of the operating characteristics of sub-optimal designs.

Version: 0.1.0
Imports: dplyr, ggplot2, logger, magrittr, methods, Rcpp, rlang, tibble, tidyr
LinkingTo: Rcpp, BH
Suggests: covr, parallel, testthat (≥ 3.0.0)
Published: 2022-10-27
Author: John Kirkpatrick ORCID iD [aut, cre]
Maintainer: John Kirkpatrick <john.kirkpatrick at>
License: GPL (≥ 3)
NeedsCompilation: yes
Language: en-GB
Materials: README NEWS
CRAN checks: mtdesign results


Reference manual: mtdesign.pdf


Package source: mtdesign_0.1.0.tar.gz
Windows binaries: r-devel:, r-release:, r-oldrel: not available
macOS binaries: r-release (arm64): mtdesign_0.1.0.tgz, r-oldrel (arm64): mtdesign_0.1.0.tgz, r-release (x86_64): mtdesign_0.1.0.tgz, r-oldrel (x86_64): mtdesign_0.1.0.tgz


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