qpNCA: Noncompartmental Pharmacokinetic Analysis by qPharmetra

Computes noncompartmental pharmacokinetic parameters for drug concentration profiles. For each profile, data imputations and adjustments are made as necessary and basic parameters are estimated. Supports single dose, multi-dose, and multi-subject data. Supports steady-state calculations and various routes of drug administration. See ?qpNCA and vignettes. Methodology follows Rowland and Tozer (2011, ISBN:978-0-683-07404-8), Gabrielsson and Weiner (1997, ISBN:978-91-9765-100-4), and Gibaldi and Perrier (1982, ISBN:978-0824710422).

Version: 1.1.5
Depends: R (≥ 3.3.0)
Imports: dplyr (≥ 0.7.0), tidyr (≥ 0.8.2), magrittr, ggplot2, knitr
Suggests: rmarkdown, markdown, covr, testthat (≥ 2.1.0)
Published: 2021-07-13
Author: Jan Huisman [aut, cre], Koen Jolling [ctb], Krina Mehta [ctb], Tim Bergsma [ctb]
Maintainer: Jan Huisman <jan.huisman at qpharmetra.com>
License: GPL-3
NeedsCompilation: no
Materials: README
CRAN checks: qpNCA results

Downloads:

Reference manual: qpNCA.pdf
Vignettes: Parameter Guidelines
A User Guide for qpNCA
Example Full NCA Analysis
Example Stepwise NCA Analysis
Package source: qpNCA_1.1.5.tar.gz
Windows binaries: r-devel: qpNCA_1.1.5.zip, r-release: qpNCA_1.1.5.zip, r-oldrel: qpNCA_1.1.5.zip
macOS binaries: r-release (arm64): qpNCA_1.1.5.tgz, r-release (x86_64): qpNCA_1.1.5.tgz, r-oldrel: qpNCA_1.1.5.tgz

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