Implementation of target-controlled infusion algorithms for compartmental pharmacokinetic and pharmacokinetic-pharmacodynamic models. Jacobs (1990) <doi:10.1109/10.43622>; Marsh et al. (1991) <doi:10.1093/bja/67.1.41>; Shafer and Gregg (1993) <doi:10.1007/BF01070999>; Schnider et al. (1998) <doi:10.1097/00000542-199805000-00006>; Abuhelwa, Foster, and Upton (2015) <doi:10.1016/j.vascn.2015.03.004>; Eleveld et al. (2018) <doi:10.1016/j.bja.2018.01.018>.
| Version: | 0.1.0 |
| Depends: | R (≥ 3.6.0) |
| Imports: | ggplot2, stats, utils, graphics, truncnorm, mvtnorm, gridExtra, reshape |
| Suggests: | testthat (≥ 2.1.0), knitr, rmarkdown, mrgsolve |
| Published: | 2021-02-26 |
| Author: | Ryan Jarrett [aut, cre] |
| Maintainer: | Ryan Jarrett <ryan.t.jarrett at vanderbilt.edu> |
| BugReports: | https://github.com/jarretrt/tci/issues |
| License: | GPL-2 |
| URL: | https://github.com/jarretrt/tci |
| NeedsCompilation: | no |
| Materials: | README |
| CRAN checks: | tci results |
| Reference manual: | tci.pdf |
| Vignettes: |
Illustration of open- and closed-loop control Introduction to tci package Simulation from a user-specified, ODE-based PK model |
| Package source: | tci_0.1.0.tar.gz |
| Windows binaries: | r-devel: tci_0.1.0.zip, r-release: tci_0.1.0.zip, r-oldrel: tci_0.1.0.zip |
| macOS binaries: | r-release: tci_0.1.0.tgz, r-oldrel: tci_0.1.0.tgz |
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