wTO: Computing Weighted Topological Overlaps (wTO) & Consensus wTO Network

Computes the Weighted Topological Overlap with positive and negative signs (wTO) networks (Nowick et al. (2009) <doi:10.1073/pnas.0911376106>) given a data frame containing the mRNA count/ expression/ abundance per sample, and a vector containing the interested nodes of interaction (a subset of the elements of the full data frame). It also computes the cut-off threshold or p-value based on the individuals bootstrap or the values reshuffle per individual. It also allows the construction of a consensus network, based on multiple wTO networks. The package includes a visualization tool for the networks.

Version: 1.2.2
Imports: data.table, igraph, magrittr, plyr, parallel, som, visNetwork, reshape2
Published: 2017-07-16
Author: Deisy Morselli Gysi, Andre Voigt, Tiago Miranda Fragoso, Eivind Almaas and Katja Nowick.
Maintainer: Deisy Morselli Gysi <deisy at bioinf.uni-leipzig.de>
License: GPL-2
NeedsCompilation: no
CRAN checks: wTO results

Downloads:

Reference manual: wTO.pdf
Package source: wTO_1.2.2.tar.gz
Windows binaries: r-devel: wTO_1.2.2.zip, r-release: wTO_1.2.2.zip, r-oldrel: wTO_1.2.2.zip
OS X El Capitan binaries: r-release: wTO_1.2.0.tgz
OS X Mavericks binaries: r-oldrel: wTO_1.2.2.tgz
Old sources: wTO archive

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